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Phase: ongoing - Le promoteur: Centre for Health Science (UK)
Centre for Health Science (UK) MAJ Il y a 4 ans

Effects of intravascular contrast media on platelet function in patients undergoing coronary angiography Background and study aims Thousands of patients each year require a test called a coronary angiogram. This test uses X-rays and dye (contrast) to provide cardiologists with detailed pictures of the heart arteries. There are several types of X-ray dyes used but all have the ability to cause harm and there is a small risk associated with an angiogram procedure. The two most commonly used dyes are Omnipaque and Vispaque. These is no agreement as to which is best and many centres (such as Raigmore) use both. Heart attacks and strokes are more likely if patients have ‘sticky’ blood. The purpose of this study is to find out the effects of these two dyes on the stickiness of blood. This may help doctors in the future decide which is the best dye in which patients. Who can participate? Patients who are undergoing a coronary angiogram can participate. What does the study involve? This study involves giving blood samples. This will require two blood samples taken at the start and the end of the procedure from an artery and a vein (a total of four blood samples). As you will have a small tube in both the artery and the vein as a normal part of your procedure, this will not involve any additional needles. After you have given these blood samples, the blood will be taken to the laboratory. You will not undergo any further procedures as part of this study and participation in this study will in no way change the treatment you receive. What are the possible benefits and risks of participating? There are no benefits to you taking part in this study. However, the information we get might help improve the future studies and treatment of heart patients. This study involves only the taking of an extra blood sample and no additional needles or procedures and therefore we would not expect any risk to the study participants. Where is the study run from? The study is being run by the NHS (UK) and University of the Highlands and Islands (UK). When is the study starting and how long is it expected to run for? March 2011 to March 2013. Who is funding the study? Funding for this study is from NHS Highland endowments, UK. Who is the main contact? Prof. Stephen Leslie [email protected]

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